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Research: NU Cancer



Title: Phase II Trial of Progressive Resistance Training with Megesterol Acetate for the Treatment of Cancer-related Weight Loss
Funding Source: Bristol-Meyers Squibb
Start Date: January 1, 1999
Length: 15 months; 3 Month Set-Up, 12 Months Full Trial
Funding: $175,000 (RIC Component: $46,000)
Description:

Currently, a joint effort between the RIC's Center for Health and Fitness and the Northwestern Medical Oncology Department is conducting a study related to the effects of the strength training on the fatigue levels of terminal cancer patients in conjunction with taking an appetite stimulant drug, Megesterol Acetate (MA). The strength training program requires a 3 hour commitment per week for 12 weeks. This trial will include 15 subjects over a one year period. In addition to measuring fatigue levels of cancer patients, other evaluations included in the study are body composition, maximal oxygen consumption (VO2 max), one repetition maximum, and timed stair climbing.




Title: Phase III Trial of Progressive Resistance Training Versus Progressive Resistance Training Plus Procrit for the Treatment of Cancer-related Fatigue
Funding Source: Ortho Biotech
Start Date: January 1, 1999
Length: 15 Months; 3 Month Set-Up, 12 Months Full Trial
Funding: $215,000 (RIC Component: $43,000)
Description:

RIC's Center for Health and Fitness and the Northwestern Medical Oncology Department is conducting a second study to test the effectiveness of the drug, Procrit. This study will investigate the effects of a 12 week strength and cardiovascular training program on fatigue levels of cancer patients taking Procrit. Procrit increases erythropoietin and hemoglobin levels in patients suffering from anemia exacerbated by chemotherapy and other cancer treatments. In addition to measuring fatigue levels of 30 cancer subjects, body composition, maximal oxygen consumption (VO2 max), one repetition maximum, and timed stair climbing will be considered.